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    Publications, Research & Media

Invited presentations (last 5 years)

2019 Manchester Paediatric neurology study day. ‘Optic neuritis in children’.
2019 Royal College of Ophthalmologists annual meeting, Glasgow. ‘Paediatric uveitis-holistic care and transition to adult services’.
2019 Manchester Foundation Trust  Educators conference ‘Implementing changes following the GMC survey’
2019 Sheffield Inflammatory Eye Disease Study day. ‘How to avoid adverse outcomes in complex uveitis’.
2019 British Association of Paediatric TB meeting, Manchester. ‘Changes in screening and ethambutol toxicity’.
2018 Women in Vision UK meeting, Liverpool. ‘The ocular phenotype of metabolic disease in children’
2018 Royal Society of Medicine, London. Squint Forum ‘Strabismus syndromes’
2018 Keynote speaker at Northern Hospitals Inflicted head trauma peer review day, Manchester ‘OCT (optical coherence tomography) and the interpretation of retinal findings in suspected inflicted head trauma’
2018 Mucopolysaccharidosis and the eye, MPS study day, Nowgen Manchester
2018 ‘Ophthalmic aspects of MPS’ MPS Masterclass Belgrade
2018 ‘Anatomy, physiology and diagnosis of Vision problems in MPS’. MPS and the five senses, Lisbon
2018 ‘Paediatric Uveitis’ North of England Ophthalmological Society meeting, Bolton
2018 ‘Eyes, a window to cystinosis’ Cystinosis Forum, London
2018 ‘Understanding the MPS1 eye and surgical interventions’ MPS Society meeting Northampton
2018 European Reference Network for rare Eye diseases (EYE-ERN), Florence. ‘Genomic testing in a busy paediatric setting’
2018 Welsh Orthoptic and Paediatric Ophthalmology conference, Cardiff ‘Ocular manifestations of inherited Metabolic disease in children’
2018 BIPOSA Manchester Chaired session on ‘Investigation of Swollen optic nerves’
2018 EyeNews meeting ‘What not to miss in Paediatric Ophthalmology’
2018 ‘Genetic testing in Paediatric Eye Disease’ British and Ireland Orthoptic Society meeting, Brighton
2017 Lifeline Express conference Ghanghzou and Xian, China- lectures on Metabolic disease and the eye, childhood cataracts, uveitis and retinopathy of prematurity.
2017 ‘MPS and the eye’, MPS study day,  Nowgen Manchester
2017 Roper-Hall alumnus meeting, Birmingham ‘Neurometabolic Disease and the eye’
2017 Ophthalmic Imaging Society Conference, Stratford upon Avon. Keynote Speaker ‘Imaging in Paediatric Ophthalmology’
2017 British and Irish Paediatric Ophthalmology Society annual meeting Hull, ‘Managing complications in paediatric uveitis’ and ‘OCT cases’
2017 MPS masterclass meeting, Biomarin Ltd, Dubai
2017 Royal College of Ophthalmologists Advanced Training the Trainers ‘The effect of the new contract on delivering training’
2017 MPS Society conference Coventry ‘Fabry manifestations in the eye’ and ‘Ophthalmic presentations in MPS conditions’
2017 Royal College of Ophthalmologists Annual Congress Liverpool workshop ‘Practical Genetics’
2016 Royal College of Ophthalmologists Paediatric Retina study day ‘Interesting cases’
2016 ‘Ophthalmic manifestations of MPSVI and how to treat’ MPS Society meeting, Northampton
2016 Ocular complications in MPS, MPS masterclass, Dubai
2016 Vision in Cerebral Palsy, Cerebral palsy network, Manchester

Book Chapters

‘Neurometabolic Disorders and the eye’. Ashworth and Morris. In Paediatric Ophthalmology and Strabismus Ed Lambert and Lyons 5th edition.
Perioperative care of the child with congenital cataract-intraoperative and post-operative medication. Ashworth and Biswas in Congenital Cataract Lloyd and Lambert 2016.
Intraocular lens implantation in the capsular bag and posterior capsulotomy techniques Ashworth and Lloyd in Congenital Cataract Lloyd and Lambert. 2016
‘Neurometabolic Disorders and the eye’. Ashworth, Morris and Wraith. In Paediatric Ophthalmology and Strabismus Ed Hoyt and Taylor 4th edition 2013

Publications (last 5 years)

Diagnosis and management of individuals with Fetal Valproate Spectrum Disorder; a consensus statement from the European Reference Network for Congenital Malformations and Intellectual Disability.

Clayton-Smith J, Bromley R, Dean J, Journel H, Odent S, Wood A, Williams J, Cuthbert V, Hackett L, Aslam N, Malm H, James G, Westbom L, Day R, Ladusans E, Jackson A, Bruce I, Walker R, Sidhu S, Dyer C, Ashworth J, Hindley D, Diaz GA, Rawson M, Turnpenny P.
Orphanet J Rare Dis. 2019 Jul 19;14(1):180

Management of paediatric ocular inflammatory disease in the UK: a national survey of practice.

Solebo AL, Rahi JS, Edelsten C, Ashworth JL, Dick AD; Paediatric Ocular Inflammation Group.
Eye (Lond). 2019 Jul 9. d

An update on the modern management of paediatric uveitis.

Choi J, Hawley DP, Ashworth J, Edelsten C, Bossuyt ASAM.
Br J Ophthalmol. 2019 Jul 4

Traboulsi syndrome due to ASPH mutation: an under-recognised cause of ectopia lentis.

Kulkarni N, Lloyd IC, Ashworth J, Biswas S, Black GCM, Clayton-Smith J; NIHR BioResource Consortium.
Clin Dysmorphol. 2019 Jul 3. 

Recommendations for the management of MPS IVA: systematic evidence- and consensus-based guidance.

Akyol MU, Alden TD, Amartino H, Ashworth J, Belani K, Berger KI, Borgo A, Braunlin E, Eto Y, Gold JI, Jester A, Jones SA, Karsli C, Mackenzie W, Marinho DR, McFadyen A, McGill J, Mitchell JJ, Muenzer J, Okuyama T, Orchard PJ, Stevens B, Thomas S, Walker R, Wynn R, Giugliani R, Harmatz P, Hendriksz C, Scarpa M; MPS Consensus Programme Steering Committee; MPS Consensus Programme Co-Chairs.
Orphanet J Rare Dis. 2019 Jun 13;14(1):137.

Recommendations for the management of MPS VI: systematic evidence- and consensus-based guidance.

Akyol MU, Alden TD, Amartino H, Ashworth J, Belani K, Berger KI, Borgo A, Braunlin E, Eto Y, Gold JI, Jester A, Jones SA, Karsli C, Mackenzie W, Marinho DR, McFadyen A, McGill J, Mitchell JJ, Muenzer J, Okuyama T, Orchard PJ, Stevens B, Thomas S, Walker R, Wynn R, Giugliani R, Harmatz P, Hendriksz C, Scarpa M; MPS Consensus Programme Steering Committee; MPS Consensus Programme Co-Chairs.
Orphanet J Rare Dis. 2019 May 29;14(1):118.

Determining the needs of ophthalmic trainees entering into specialist training and how they can be met.

Walkden A, Young JF, Spencer AF, Ashworth J.
Adv Med Educ Pract. 2019 Apr 17;10:201-206.

Areas of agreement in the management of childhood non-infectious chronic anterior uveitis in the UK.

Solebo AL, Rahi JS, Dick AD, Ramanan AV, Ashworth J, Edelsten C; Members of the POIG Uveitis Delphi Group.
Br J Ophthalmol. 2019 May 2

Congenital cataracts in females caused by BCOR mutations; report of six further families demonstrating clinical variability and diverse genetic mechanisms.

Redwood A, Douzgou S, Waller S, Ramsden S, Roberts A, Bonin H, Lloyd IC, Ashworth J, Black GCM, Clayton-Smith J.
Eur J Med Genet. 2019 Apr 30

An ontological foundation for ocular phenotypes and rare eye diseases.

Sergouniotis PI, Maxime E, Leroux D, Olry A, Thompson R, Rath A, Robinson PN, Dollfus H; ERN-EYE Ontology Study Group.
Orphanet J Rare Dis. 2019 Jan 9;14(1):8

Ophthalmology research in the UK's National Health Service: the structure and performance of the NIHR's Ophthalmology research portfolio.

Dawson SR, Linton E, Beicher K, Gale R, Patel P, Ghanchi F, Beresford MW, Poustie V, Chakravarthy U, Bourne RRA; NIHR Ophthalmology Specialty Group.
Eye (Lond). 2018 Nov 20.

Variability in the ocular phenotype in mucopolysaccharidosis.

Sornalingam K, Javed A, Aslam T, Sergouniotis P, Jones S, Ghosh A, Ashworth J.
Br J Ophthalmol. 2018 Aug 17

Lathosterolosis: A Relatively Mild Case with Cataracts and Learning Difficulties.

Anderson R, Rust S, Ashworth J, Clayton-Smith J, Taylor RL, Clayton PT, Morris AAM.
JIMD Rep. 2018 Aug 11. 

Incidence, management and outcome of raised intraocular pressure in childhood-onset uveitis at a tertiary referral centre.

Tan SZ, Yau K, Steeples LR, Ashworth J, Fenerty C, Jones N.
Br J Ophthalmol. 2018

Retinopathy of prematurity in the United Kingdom: retreatment rates, visual and structural 1-year outcomes.

Adams GG, Bunce C, Xing W, Butler L, Long V, Reddy A, Dahlmann-Noor AH; UK Retinopathy of Prematurity Special Interest Group.
Eye (Lond). 2018 Jul 16. 

Varicella-zoster virus necrotising retinitis, retinal vasculitis and panuveitis following uncomplicated chickenpox in an immunocompetent child.

Yu J, Ashworth J, Hughes S, Jones N.
BMJ Case Rep. 2018 Apr 5;2018.

Nonaccidental injury presenting as unilateral retinal detachment in two infants.

Sornalingam K, Borman AD, Ashworth J.
J AAPOS. 2018 Jun;22(3):231-233. 

The effect of haemopoietic stem cell transplantation on the ocular phenotype in mucopolysaccharidosis type I (Hurler). 
Javed A, Aslam T, Jones SA, Mercer J, Tyler K, Church H, Ghosh A, Wynn R, Sornalingam K, Ashworth J.Acta Ophthalmol. 2017 Dec 14. doi: 10.1111/aos.13627.
Craniofacial linear scleroderma associated with retinal telangiectasia and exudative retinal detachment. 
Lenassi E, Vassallo G, Kehdi E, Chieng AS, Ashworth JL.
J AAPOS. 2017 Jun;21(3):251-254. 

Panel-Based Clinical Genetic Testing in 85 Children with Inherited Retinal Disease.

Taylor RL, Parry NRA, Barton SJ, Campbell C, Delaney CM, Ellingford JM, Hall G, Hardcastle C, Morarji J, Nichol EJ, Williams LC, Douzgou S, Clayton-Smith J, Ramsden SC, Sharma V, Biswas S, Lloyd IC, Ashworth JL, Black GC, Sergouniotis PI.
Ophthalmology. 2017 Jul;124(7):985-991.

Objective Quantification of Changes in Corneal Clouding Over Time in Patients With Mucopolysaccharidosis. 
Javed A, Aslam T, Jones SA, Ashworth J.
Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):954-958. 

Improving diagnosis for congenital cataract by introducing NGS genetic testing.

Musleh M, Ashworth J, Black G, Hall G. BMJ Qual Improv Rep. 2016 Sep 19;5(1).

Outcomes of Long-Term Treatment with Laronidase in Patients with Mucopolysaccharidosis Type I.

Laraway S, Mercer J, Jameson E, Ashworth J, Hensman P, Jones SA.
J Pediatr. 2016 Nov;178:219-226.e1

Outcomes of keratoplasty in the mucopolysaccharidoses: an international perspective.

Ohden KL, Pitz S, Ashworth J, Magalhães A, Marinho DR, Lindahl P, Teär Fahnehjelm K, Summers CG.
Br J Ophthalmol. 2016 Sep 28

Diagnosing the cause of bilateral paediatric cataracts: comparison of standard testing with a next-generation sequencing approach.

Musleh M, Hall G, Lloyd IC, Gillespie RL, Waller S, Douzgou S, Clayton-Smith J, Kehdi E, Black GC, Ashworth J.
Eye (Lond). 2016 Sep;30(9):1175-81.

Use of new imaging in detecting and monitoring ocular manifestations of the mucopolysaccharidoses.

Javed A, Aslam T, Ashworth J.
Acta Ophthalmol. 2016 Jun 8. 

Atypical presentation of CRB1 retinopathy.

Morarji J, Lenassi E, Black GC, Ashworth JL.
Acta Ophthalmol. 2016 Sep;94(6):e513-4.

Automated Measurement of Visual Acuity in Pediatric Ophthalmic Patients Using Principles of Game Design and Tablet Computers.

Aslam TM, Tahir HJ, Parry NR, Murray IJ, Kwak K, Heyes R, Saleh MM, Czanner G, Ashworth J.
Am J Ophthalmol. 2016 Aug Epub ahead of print

Optic neuropathy in methylmalonic acidemia and propionic acidemia. Martinez Alvarez L, Jameson E, Parry NR, Lloyd C, Ashworth JL. Br J Ophthalmol. 2016 Jan;100(1):98-104

Next-generation Sequencing in the Diagnosis of Metabolic Disease Marked by Pediatric Cataract. Gillespie RL, Urquhart J, Anderson B, Williams S, Waller S, Ashworth J, Biswas S, Jones S, Stewart F, Lloyd IC, Clayton-Smith J, Black GC. Ophthalmology. 2016 Jan;123(1):217-20.

International Conferences

2019 AAPOS San Diego, USA
2019 MPS Masterclass Budapest
2019 Paediatric Ophthalmology conference Beijing, China
2018 Organised and chaired British and Ireland Paediatric Ophthalmology Strabismus Association meeting, Manchester
2018 European Reference Network for rare Eye diseases (EYE-ERN), Florence. 
2018 MPS Masterclass Florence and Belgrade
2017 Paediatric Ophthalmology Conference, Guangzhou, China
2017 MPS Masterclass, Dubai
2016 American Association of Paediatric Ophthalmology and Strabismus (AAPOS), Vancouver
2016 14th International MPS meeting, Bonn
2015 UK Eye Genetics Group meeting, Manchester MPS Masterclass, Istanbul British and Ireland Paediatric Ophthalmology Society meeting, Cardiff
2014 European Paediatric Ophthalmology Society, Barcelona; AAPOS Palm Springs 2014;
2013 AAPOS Boston 2013 BIPOSA, Leeds
2011 MPS VI and the Eye - South American MPS VI meeting, Salvador Brazil (sponsored by Biomarin)


2016 Your Child In Their Hands’ - Channel 5
2015 ‘Newsround’ - CBBC
2014 Operation Ouch’ - CBBC

Dr Jane L. Ashworth BMBCh FRCOphth PhD

Consultant Ophthalmic Surgeon & Paediatric Ophthalmologist

  • Manchester Royal Eye Hospital
    Private Patient Centre, Manchester M13 9PL
  • Cheshire Eye Clinic, Wilmslow SK9 1PA
  • Tel : 07946 326 614